Pharmacotherapy for depression should consist of acute therapy up until the best clinical response or remission is achieved usually 6 12 weeks and continuation therapy for a further six months to prevent relapse sometimes maintenance therapy will continue for months or years in case of recurrent or persistent disorders. Comprehensive and state of the art the second edition of pharmacotherapy of depression offers major revisions of every chapter and the addition of new chapters by expert contributors the first chapter reviews the neurobiology of depression which lays the groundwork for understanding the mechanisms of action of antidepressants. Pharmacotherapy of major depressive disorder charles h brown ms pharm rph cacp professor emeritus of clinical pharmacy purdue university college of pharmacy west lafayette indiana us pharm 20113611hs3 hs8 depression can strike anyone regardless of age ethnic background socioeconomic status or gender major depressive disorder mdd is a mental disorder characterized by an all . In pharmacotherapy of depression well recognized clinician scientists who have worked extensively in both basic and clinical research as well as in clinical practice explain in detail the welter of therapeutic options available to frontline physicians who prescribe antidepressants single mindedly concentrating on information of high relevance to their daily clinical use the authors review
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