Molecular diagnostic tests detect specific biologic molecules or biomarkers in a patients tissue and fluid samples molecular diagnostic tests can be used to select a cancer therapy and or to monitor the effects of a treatment based on characteristics of or changes in the biomarker. This special issue of genetics research international focuses on molecular genetics and cytogenetics in cancer the hunt for informative disease related genetic biomarkers may become so valuable for the differential diagnosis prognosis and disease monitoring of cancer patients that numerous researchers are committed to this challenge indeed a colossal effort of current molecular medicine . Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction qpcr sequence specific oligonucleotide arrays next generation sequencing ngs cgh arrays and methodologies directed at the detection of epigenetic events high throughput nucleic acid and protein arrays direct sequencing and fish based methodologies currently used in the diagnosis of solid tumors. Additional physical format online version molecular genetics in cancer diagnosis new york elsevier c1990 ocolc606910642 document type book
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